Preparative Separation Typically medicinal cannabis production involves an initial extraction from the flower bud material using Supercritical Fluid Extraction (SFE), solvent extraction or similar technique to produce a concentrate of terpenes and cannabinoids. The basic SFC system comprises a high-pressure liquid CO2 pump, co-solvent pump (for gradient work), separation column, typically a cellulose column with […]

Cannabinoid Analytical Separations Cannabinoid Analytical and Preparative Separations Supercritical Fluid Chromatography (SFC) is a relatively new technique that offers several advantages including faster run times, better resolution and more concentrated separations. The limitations of SFC are: it has only been proven on small molecular groups and gradient development is more complicated than for HPLC. The […]