Before developing the methods to extract cannabinoids from cannabis plant material, there are a number of steps that will need to be understood and implemented. Plant material with the desired chemical characteristics (e.g. the most appropriate cannabinoid profile) will need to be chosen. This may involve the selective breeding of premium plants or the purchase […]
28
Jun
Jun
Preparative Separation Typically medicinal cannabis production involves an initial extraction from the flower bud material using Supercritical Fluid Extraction (SFE), solvent extraction or similar technique to produce a concentrate of terpenes and cannabinoids. The basic SFC system comprises a high-pressure liquid CO2 pump, co-solvent pump (for gradient work), separation column, typically a cellulose column with […]
28
Jun
Jun
Cannabinoid Analytical Separations Cannabinoid Analytical and Preparative Separations Supercritical Fluid Chromatography (SFC) is a relatively new technique that offers several advantages including faster run times, better resolution and more concentrated separations. The limitations of SFC are: it has only been proven on small molecular groups and gradient development is more complicated than for HPLC. The […]